Phylogenetic Methods and its
Applications by Geetika Munjal in Open Access Biostatistics &Bioinformatics
The phylogenetic tree portrays a
relationship between sets of species and represents a model of molecular
evolution. The current forms of species retain many of their ancestral
features, some of which gradually change to help these species adjust to their
environment. We provide a review of phylogenetic construction and validation
methods and its application in cancer analysis. The need of alignment free
methods for sequence comparison is also explored as an alternative to alignment
based methods.
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