Sunday 29 September 2019

String Matching in DNA Databases- Crimson Publishers

String Matching in DNA Databases by Yangjun Chen in Open Access Biostatistics & Bioinformatic: Crimson Publishers- Crimson Publishers Open Access Journal


The recent development of next-generation sequencing has changed the way we carry out the molecular biology and genomic studies. It has allowed us to sequence a DNA (Deoxyribonucleic acid) sequence at a significantly increased base coverage, as well as at a much faster rate [1]. This facilitates building an excellent platform for a whole genome sequencing, and for a variety of sequencing-based analyses, including gene expressions, mapping DNA-protein interactions, whole-transcriptome sequencing, and RNA (Ribonucleic acid) splicing profiles. For example, the RNA-Seq protocol [2], in which processed mRNA is converted to cDNA and then sequenced, is enabling the identification of previously unknown genes and alternative splice variants. The whole-genome sequencing of tumour cells can uncover previously unidentified cancer-initiating mutations.

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Tuesday 24 September 2019

Bioinformatics: An Introduction- Crimson Publishers

Bioinformatics: An Introduction by Nidhi Mishra in Open Access Biostatistics & Bioinformatic: Crimson Publishers- Open Access Biostatistics & Bioinformatics journals


An unprecedented revolution has been observed in science with recent technological advances, which have provided a large amount of “omic” data. The crescent generation and availability of this information available in public databases were, and still are, a challenge for professionals from different areas. However, what is the challenge? In biology, the main challenge is to make sense of the enormous amount of structural data and sequences that have been generated at multiple levels of biological systems. Still, in bioinformatics, development of tools is necessary (statistical and computational) capable of assisting in understanding the mechanisms underlying biological questions in the study. Besides, if we consider the complexity of science, this is a highly reductionist view. The era of a “new biology” emerges accompanied by the birth/development of other sciences, such as bioinformatics and computational biology, which have an integrated interface of molecular biology.

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Friday 13 September 2019

Students’ Home Activities and Academic Performance in Economics in Senior Secondary School II in Isoko South Local Government Area of Delta State- Crimson Publishers

Students’ Home Activities and Academic Performance in Economics in Senior Secondary School II in Isoko South Local Government Area of Delta State by Kingsley Akarowhe in Open Access Biostatistics & Bioinformatic- Crimson Publishers: Bioinformatics Open Access Journals



This study investigated the influence of students’ home activities on their academic performance in Economics in senior secondary school II in Isoko South Local Government Area of Delta State. Three research questions were answered in the study and three null hypotheses were tested at .05 level of significance. The population of the study consisted of 1,130 senior secondary school II in Isoko South Local Government Area of Delta State. A sample size of 113 students was adopted; this was 10 percent of the entire population. A 21 structured questionnaire was used to elicit responses from the respondents (students). The questionnaire was face-validated by experts in Faculty of Education, University of Uyo. Cronbach’s Alpha Technique was used in determining the reliability of the instrument and a correlation coefficient of 0.76 was obtained.

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