Structural Bioinformatics: A Brief Overview by
Long Pei in Open Access Biostatistics & Bioinformatics: Crimson Publishers-
Bioinformatics Open Access Journals
In the past decades, many advanced
bio-technologies have accelerated frontier research to explore biological
systems including cell, the basic unit of life. Experimental exploration of
cellular environment, however, will be difficult as it requires not only huge
labor efforts and costs but also large number of samples for reproducible
research. With large volume of available biological data generated,
bioinformatics becomes an important hybrid science subject to support
systematic and comprehensive data storage, processing and analysis. In joint
with statistics and algorithms, biological data such as DNA sequences have been
more efficiently processed by bioinformatics methods. Unlike sequential data,
biological structures are usually more dynamic and stochastic, thus, structural
biology is more challenging a task for bioinformatics.
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