Differential Mathematical Models of Intellectu- alization of Fast Flow Processes on Railway Elec- tricity Supply Networks

 

Abstract

The problem of innovative transformation of railway power supply networks Is Investigated and the direction of researchrelates to the organization of differential mathematical models of optimization of procedures by control of high-speed technological processes of power supply of railways. A graphis proposed, whose logical structure adequately reflects the architecture of the computerized network for managing the power supply system and developed its differential mathematical model. On the basis of the principle of minimax, the optimal strategy of intellectualization of the power supply processes in each of the nodes of the computer network was developed for the cases of the worst combination of the intensity of the requests and the intensity of their service. Hereis a way to ensure that the specified performance of the individual no desands egments of theintelligent computer control network by exploring the extremum off unctionality, implemented in the field of T-images using differential spectra.

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Maximum Entropy Risk Model for Investment Management

Abstract

In the present communication Markowitz’s method of mean- variance efficient frontier has been explained. Some introductory entropy models and concepts related to risk in investments have been discussed. Risk aversion index and Pareto-optimal sharing of risk have been defined. A new measure of risk based on maximum entropy principle has been studied in detail. Mathematics Subject Classification 2000: 91b24 and 94a15.

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Genomics of Newly Discovered Leprosy Pathogen: Mycobacterium lepromatosis and Its Geographic Isolation in Mexico

Overview

Leprosy is a chronic dermatologic infection that has plagued human populations for thousands of years. Mycobacterium leprae, the etiological agent for leprosy, has puzzled scientists since its identification by Hansen in 1873 [1]. Leprosy is one of the leading causes of treatable neuropathy [2]. It has been affecting mankind since the earliest historically recorded identification and far beyond (2000 B.C, in ancient Indus civilization) [3]. Leprosy is also one of the earliest recognized diseases which have a proven association with the bacterial pathogen, M. leprae [3]. In 2008, a new bacterium, M. lepromatosis was discovered in Mexico which was also reported to cause leprosy [4]. M. lepromatosis was found to be associated with a typical severe form of lepromatous leprosy (LL), called Diffuse Lepromatous Leprosy (DLL) which is usually seen in the Americas [5-7]. DLL is characterized by an unusual form of immune reaction against the pathogen, called Lucio’s phenomenon, characterized by diffuse, non-nodular cutaneous infiltration with sharply demarcated skin lesions, which often gets infected to result in life threatening situations [8,9].

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COVID-19 Epidemic: China and ex-China

 

Abstract

Here we report the current COVID-19 epidemic in terms of mortality and recovery compared to the confirmed patient population of provinces in China as well as countries outside of China. Data was obtained from the Center for System Science and Engineering (CSSE) by Johns Hopkins University (JHU) and was plotted in log-log charts. For China, mortality dropped as low as 0.08% but then converged to a band of 1%-5%, with the median value of 1.1% as of March 9th, 2020. For countries outside of China, mortality dropped to a low of 0.2% with a median value of 2.4% as of March 9th, 2020. This difference was statistically significant with p=0.0057.A bi-modal distribution in mortality was observed for both China and countries outside of China, which would concur with reports mentioning two possible strains of the SARS-CoV-2 virus. China exhibited a median recovery rate of 95.0% with the lowest being Hubei province with a recovery rate of 57%. Outside of China, the median recovery rate was 10.7% and was significantly lower than that of China, p <0.0001, t-test. Distribution-wise, both China and countries outside of China were observed to be similar. As of now, the spread of COVID-19 in countries outside of China are showing properties more similar to that of Hubei–the epicenter of COVID-19 epidemic in China.

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Detection of protein complexes in blood plasma synthesized by malignant glioma cells and their microenvironment by dynamic light scattering depending on the degree of the blood-brain barrier permeability_Crimson Publishers

Detection of protein complexes in blood plasma synthesized by malignant glioma cells and their microenvironment by dynamic light scattering depending on the degree of the blood-brain barrier permeability by Gridina NYa in Open Access Biostatistics & Bioinformatics

In the blood plasma of patients with malignant gliomas of the brain by method dynamic light scattering protein complexes with diameter of more than 150nm were detected, indicating increased permeability of the blood brain/tumor (BBTB) and blood-brain (BBB) barriers. The results of these studies are taken as the basis for the development of the express method for determining the increased permeability of the BBTB and BBB in neurosurgical patients. The method can be used at a certain stage of chemotherapy for patients with malignant gliomas of the brain, depending on the permeability of the BBTB and BBB.

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Modeling of Capture Fisheries and Effectiveness of the Current Gear Restriction: The Case of Lake Tana, Ethiopia_Crimson Publishers

 Modeling of Capture Fisheries and Effectiveness of the Current Gear Restriction: The Case of Lake Tana, Ethiopia by Erkie A in Open Access Biostatistics & Bioinformatics

Following the exponentially increased demand for fishes, magnificent number of individuals are participated in various stages of capture fisheries in order to improve their livelihood. However, in Lake Tana fisheries, regulations related to gear restriction (fishing net and mesh size), destructive way of fishing, closing of spawning season and site, and amount of harvest are a loosely (almost not) regulated. This is attributed to weak institutions that have no incentives for fishers to manage efficiently in a way that maximized their present and future benefits. As a management framework, fishing gear restriction reduces the burden on the open access fishery and endangered species. On the other hand, ITQs encourage increased responsibility and accountability by quota owners for management and enhancement of the fishery resource. In this regard, ITQs is more efficient than gear restriction because of it creates sense of ownership and its flexibility in providing stable and profitable market.

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Comparison of Tuberculosis, Measles, Poliomyelitis and Rubella on Children Aged Less than 15 in a Poor Country: Case of the Republic of Pakistan_Crimson Publishers

 Comparison of Tuberculosis, Measles, Poliomyelitis and Rubella on Children Aged Less than 15 in a Poor Country: Case of the Republic of Pakistan by İlker Etikan in Open Access Biostatistics & Bioinformatics

We compared Measles, Tuberculosis, Poliomyelitis and Rubella infectious diseases in Pakistan on children aged less than 15 years from 2013 to 2018. We collected the registered cases of each disease per years at the World Health Organization (WHO) and at the United Nation International Children Emergency Fund (UNICEF) website and we used SPSS program to calculate descriptive statistics and plot graphics. We find out that over the past six years, among the four infectious diseases studied, Tuberculosis and Measles were the most present among children aged fewer than 15, their mean over the years was respectively 34430.50 and 20107.50, and their percentage was around 50% Of the whole studied diseases. Rubella and Poliomyelitis were the less infectious disease present among children aged under 15 in Pakistan from 2013 to 2018, their mean over the years was respectively 178.35 and 114.28, and their percentage was around 1% of the whole studied infectious diseases. Furthermore, Away from Poliomyelitis which curve was mostly decreasing over the last six years, all the three other diseases, Tuberculosis, Measles and Rubella had a curve mostly increasing over the last six years.

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